I've scanned everything from half frame to 6x9, and after a fair bit of experimentation, I scan everything at the highest real resolution my scanner can manage, which in real terms means scanning at 2400ppi. Does it make that much difference? I haven't done any empirical tests, but I know that the more I have to work with, the better my postprocessing results are. I haven't done a lot of printing yet, but I'm willing to assume that this can only translate to higher potential quality in the final print.