My wife, Lara, and I drove Route 66 last October. We were a bit paranoid about travelling light as we'd be in and out of hotels, living out of a suitcase. As a result, I took 2 Nikon bodies and 4 small prime lenses + 20 rolls of film. Don't get me wrong, I'm generally happy with the results. However, if weight and ultimate convenience isn't at a premium, the extra quality that the blad will provide is worth the difference. If I were arranging the Route 66 holiday again, I'd take my 500c/m, 50, 80 and 120mm lenses, 3 backs, Pentax Spotmeter V and 30 rolls of film, no problem....